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17 β-Hydroxysteroid Dehydrogenase Type 13 Minimization for the Treatment of NASH (HORIZON): A Double-Blind, Placebo-Controlled Phase 2b Study to Evaluate the Efficacy and Safety of GSK4532990 in Adults With Pre-Cirrhotic Nonalcoholic Steatohepatitis

Trial Profile

17 β-Hydroxysteroid Dehydrogenase Type 13 Minimization for the Treatment of NASH (HORIZON): A Double-Blind, Placebo-Controlled Phase 2b Study to Evaluate the Efficacy and Safety of GSK4532990 in Adults With Pre-Cirrhotic Nonalcoholic Steatohepatitis

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 20 May 2025

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At a glance

  • Drugs GSK 4532990 (Primary)
  • Indications Hepatic fibrosis; Non-alcoholic steatohepatitis
  • Focus Therapeutic Use
  • Acronyms HORIZON
  • Sponsors GlaxoSmithKline; GlaxoSmithKline Research & Development; GSK

Most Recent Events

  • 11 May 2025 Planned End Date changed from 4 May 2026 to 5 Apr 2027.
  • 24 Mar 2025 Planned End Date changed from 13 Mar 2026 to 4 May 2026.
  • 24 Mar 2025 Planned primary completion date changed from 8 Dec 2025 to 26 Jan 2026.

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