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A Phase I/II, Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of Vactosertib as a Single Agent in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma

Trial Profile

A Phase I/II, Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of Vactosertib as a Single Agent in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 15 Apr 2025

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At a glance

  • Drugs Vactosertib (Primary)
  • Indications Osteosarcoma
  • Focus Adverse reactions; Proof of concept
  • Sponsors MedPacto

Most Recent Events

  • 11 Mar 2025 Planned End Date changed from 1 Nov 2025 to 1 Dec 2025.
  • 11 Mar 2025 Planned primary completion date changed from 1 Jul 2025 to 1 Sep 2025.
  • 03 May 2023 According to a MedPacto media release, 54 patients are planned to recruit in USA and Korea phase 1/2 studies.

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