Cadonilimab as Induction-adjuvant PD-1/CTLA-4 Bispecific Blockade Combined With Induction Chenotherapy and Concurrent Chemoradiotherapy in High-risk Locoregionally-advanced Nasopharyngeal Carcinoma: a Multicenter, Randomized, Controlled, Multicenter, Phase 3 Clinical Trial
Latest Information Update: 28 Jan 2025
At a glance
- Drugs Cadonilimab (Primary) ; Cisplatin (Primary) ; Gemcitabine (Primary)
- Indications Carcinoma; Nasopharyngeal cancer
- Focus Therapeutic Use
- Acronyms GEMSTONE
Most Recent Events
- 23 Jan 2025 Planned number of patients changed from 418 to 490.
- 23 Jan 2025 Planned End Date changed from 1 Jan 2027 to 1 Aug 2029.
- 23 Jan 2025 Planned primary completion date changed from 1 Jan 2025 to 1 Aug 2027.