Phase 1 Trial for Patients With Advanced Hematologic Malignancies Undergoing Reduced Intensity Allogeneic HCT With a T-cell Depleted Graft With Infusion of Conventional T-cells and Regulatory T-cells
Latest Information Update: 14 Jan 2026
At a glance
- Drugs Cyclophosphamide (Primary) ; Filgrastim (Primary) ; Fludarabine (Primary) ; Melphalan (Primary) ; Mycophenolate mofetil (Primary) ; Orca-T (Primary) ; Plerixafor (Primary) ; Ruxolitinib (Primary) ; Tacrolimus (Primary) ; Thiotepa (Primary)
- Indications Graft-versus-host disease
- Focus Pharmacodynamics; Therapeutic Use
Most Recent Events
- 19 Dec 2025 Planned End Date changed from 1 Dec 2025 to 1 Nov 2027.
- 19 Dec 2025 Planned primary completion date changed from 1 Dec 2025 to 1 Nov 2027.
- 26 Jun 2025 Planned number of patients changed from 40 to 60.