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A Phase 1, Open-label, Multicenter Study to Assess Safety, Tolerability, PK, and Efficacy of MK-6598 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

Trial Profile

A Phase 1, Open-label, Multicenter Study to Assess Safety, Tolerability, PK, and Efficacy of MK-6598 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 26 Jun 2025

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At a glance

  • Drugs MK-6598 (Primary) ; Pembrolizumab (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions
  • Sponsors Merck Sharp & Dohme Corp.

Most Recent Events

  • 19 Jun 2025 Status changed from active, no longer recruiting to completed.
  • 30 Apr 2025 Results assessing the safety, tolerability, PK, and antitumor activity of MK-6598,presented at the 116th Annual Meeting of the American Association for Cancer Research
  • 16 Apr 2025 Planned End Date changed from 13 Dec 2027 to 27 May 2025.

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