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A Global Multicenter Phase 1/2 Trial of EO4010, a Novel Microbial Derived Peptide Therapeutic Vaccine, in Combination With Nivolumab and/or Bevacizumab, for Treatment of Patients With Previously Treated Metastatic Colorectal Carcinoma

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Trial Profile

A Global Multicenter Phase 1/2 Trial of EO4010, a Novel Microbial Derived Peptide Therapeutic Vaccine, in Combination With Nivolumab and/or Bevacizumab, for Treatment of Patients With Previously Treated Metastatic Colorectal Carcinoma

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 16 Dec 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; EO 4010 (Primary) ; Nivolumab (Primary)
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Adverse reactions; First in man
  • Acronyms AUDREY
  • Sponsors Enterome
  • Most Recent Events

    • 11 Dec 2024 According to Enterome Media Release, initial clinical data from the ongoing Phase 1/2 AUDREY trial evaluating EO4010 in microsatellite stable metastatic colorectal cancer (CRC), will be presented at the ESMO Immuno-Oncology (IO) Congress, taking place in Geneva, Switzerland, December 11-13, 2024.
    • 11 Dec 2024 Results presented in the Enterome Media Release.
    • 15 Oct 2024 Bevcizumab has been added as an option to be used in combination with E04010.

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