A modular, multi-arm, first-in-human trial to evaluate the safety and tolerability of MDX-124 alone and in combination with anti-cancer treatments, in participants with locally advanced, unresectable or metastatic solid malignancies
Latest Information Update: 01 Jul 2024
At a glance
- Drugs MDX 124 (Primary) ; Gemcitabine; Paclitaxel
- Indications Bladder cancer; Cholangiocarcinoma; Colorectal cancer; Gastric cancer; Liver cancer; Lung cancer; Ovarian cancer; Pancreatic cancer; Prostate cancer; Renal cancer; Solid tumours; Triple negative breast cancer
- Focus Adverse reactions; First in man
- Acronyms ATTAINMENT
- Sponsors Medannex
Most Recent Events
- 04 Jun 2024 According to trial design presented at the 60th Annual Meeting of the American Society of Clinical Oncology, Cohorts at 1, 2.5 and 5 mg/kg have been completed without DLT and enrollment to cohort 4 (10 mg/kg) began in January 2024.
- 04 Jun 2024 Trial design presented at the 60th Annual Meeting of the American Society of Clinical Oncology.
- 01 Dec 2022 Status changed from not yet recruiting to recruiting.