A Phase 2, Adaptive, Double-blinded, Placebo Controlled, Randomized, Multi-center Trial to Evaluate the Efficacy, Safety and Tolerability of Intracoronary Infusion of AB-1002 in Adult Subjects With New York Heart Association (NYHA) Class III Heart Failure and Non-ischemic Cardiomyopathy
Latest Information Update: 15 Apr 2025
At a glance
- Drugs AB 1002 (Primary)
- Indications Cardiomyopathies; Heart failure
- Focus Adverse reactions; Therapeutic Use
- Acronyms GenePHIT
- Sponsors Asklepios BioPharmaceutical
- 13 Feb 2025 According to Bayer media release, the company announced that the first participant has been randomized in Europe in GenePHIT (Gene PHosphatase Inhibition Therapy), a Phase 2 clinical trial of AB-1002 for the treatment of congestive heart failure (CHF).
- 28 Jun 2024 Planned End Date changed from 1 Dec 2030 to 31 Dec 2030.
- 28 Jun 2024 Planned primary completion date changed from 1 Dec 2030 to 31 Oct 2026.