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A Phase 2b, Multicenter, Double-Blind, Randomized, Placebo-controlled Trial Evaluating Efficacy and Safety of Subcutaneous Doses of TransCon CNP Administered Once Weekly for 52 Weeks in Children With Achondroplasia Followed by an Open Label Extension Period

Trial Profile

A Phase 2b, Multicenter, Double-Blind, Randomized, Placebo-controlled Trial Evaluating Efficacy and Safety of Subcutaneous Doses of TransCon CNP Administered Once Weekly for 52 Weeks in Children With Achondroplasia Followed by an Open Label Extension Period

Status: Completed
Phase of Trial: Phase II/III

Latest Information Update: 23 Jun 2026

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At a glance

  • Drugs Navepegritide (Primary)
  • Indications Achondroplasia
  • Focus Registrational; Therapeutic Use
  • Acronyms ApproaCH
  • Sponsors Ascendis Pharma

Most Recent Events

  • 07 May 2026 Results published in the Media Release
  • 06 May 2026 According to an Ascendis Pharma media release, data follow previously reported Week 104 results and expand on data recently presented by M. Jennifer Abuzzahab, M.D. during PES 2026, the annual meeting of the Pediatric Endocrine Society.
  • 16 Mar 2026 Results presented in the Ascendis Pharma media release.

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