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A Phase 1 Open-Label, Single Arm Dose Escalation Study to Evaluate the Safety and Tolerability of Intravitreally Administered VP-001 in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy

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Trial Profile

A Phase 1 Open-Label, Single Arm Dose Escalation Study to Evaluate the Safety and Tolerability of Intravitreally Administered VP-001 in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 Jun 2025

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At a glance

  • Drugs VP-001 (Primary)
  • Indications Retinitis pigmentosa
  • Focus Adverse reactions; First in man
  • Acronyms Platypus
  • Sponsors PYC Therapeutics

Most Recent Events

  • 31 May 2025 Planned End Date changed from 30 Mar 2024 to 30 Aug 2025.
  • 31 May 2025 Planned primary completion date changed from 30 Mar 2024 to 30 Aug 2025.
  • 24 Feb 2025 Planned End Date changed from 30 May 2024 to 30 Mar 2024.

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