Trial Profile

A Liquid-biopsy Informed Platform Trial to Evaluate Treatment in CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 16 Jan 2025

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At a glance

Drugs Fulvestrant (Primary) ; Gemcitabine (Primary) ; Lunresertib (Primary) ; Luvixasertib (Primary) ; Niraparib (Primary)
Indications Advanced breast cancer; Male breast cancer
Focus Biomarker; Therapeutic Use

Most Recent Events

23 Oct 2024 Trial design discussed in an abstract published at 36th EORTC-NCI-AACR Symposium on molecular targets and cancer therapeutics
21 Feb 2024 Planned End Date changed from 1 Jun 2028 to 30 Jun 2028.
21 Feb 2024 Planned primary completion date changed from 1 Dec 2027 to 31 Dec 2027.

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