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A Phase 1/1b Study of Single and Multiple Ascending Doses of TLC 6740 in Healthy Subjects, Including Evaluation of Food Effect and Potential Drug-Drug Interactions, and Preliminary Safety and Efficacy in Subjects with Obesity, with or Without Diabetes

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Trial Profile

A Phase 1/1b Study of Single and Multiple Ascending Doses of TLC 6740 in Healthy Subjects, Including Evaluation of Food Effect and Potential Drug-Drug Interactions, and Preliminary Safety and Efficacy in Subjects with Obesity, with or Without Diabetes

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 19 Feb 2025

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At a glance

  • Drugs TLC 6740 (Primary) ; TLC 6740 (Primary)
  • Indications Diabetes mellitus; Lipodystrophy; Metabolic disorders; Non-alcoholic steatohepatitis; Obesity
  • Focus Adverse reactions; First in man; Pharmacokinetics
  • Sponsors OrsoBio

    • Most Recent Events

    • 12 Feb 2025 Planned number of patients changed from 341 to 506.
    • 12 Feb 2025 Planned End Date changed from 1 Mar 2025 to 1 Aug 2025.
    • 12 Feb 2025 Planned primary completion date changed from 1 Jan 2025 to 1 Jun 2025.

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