Trial Profile

A Phase 1, Open-Label, 4-Part, Fixed-Sequence Study to Assess the Effect of Itraconazole, a Strong CYP3A Inhibitor, the Effect of Fluconazole, a Moderate CYP3A/2C9 Inhibitor, the Effect of Rifampin, a Strong CYP3A Inducer, and the Effect of Rabeprazole, a Proton Pump Inhibitor on the Pharmacokinetics of HMPL-689 in Healthy Volunteers

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 08 Mar 2024

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At a glance

Drugs Amdizalisib (Primary) ; Fluconazole (Primary) ; Itraconazole (Primary) ; Rabeprazole (Primary) ; Rifampicin (Primary)
Indications Follicular lymphoma; Lymphoma; Marginal zone B-cell lymphoma
Focus Pharmacokinetics
Sponsors HUTCHMED

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