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A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Investigate the Efficacy and Safety of Furmonertinib Compared to Platinum-Based Chemotherapy as First-Line Treatment for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations (FURVENT)

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Trial Profile

A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Investigate the Efficacy and Safety of Furmonertinib Compared to Platinum-Based Chemotherapy as First-Line Treatment for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations (FURVENT)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 25 Apr 2025

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At a glance

  • Drugs Firmonertinib (Primary) ; Carboplatin; Cisplatin; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms FURVENT
  • Sponsors ArriVent Biopharma

Most Recent Events

  • 22 Apr 2025 Status changed from recruiting to active, no longer recruiting.
  • 03 Mar 2025 According to an ArriVent Biopharma media release, earlier this year trial reached its target enrollment . Top-line data in 2025 and expects to provide an update on timing of the top-line Phase 3 data release in Q2 2025.
  • 14 Aug 2024 According to an ArriVent Biopharma media release, the topline data from this trial expected in 2025.

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