A Phase 2 Trial of Combination Therapies With Adagrasib in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation
Latest Information Update: 10 Oct 2024
At a glance
- Drugs Adagrasib (Primary) ; Carboplatin (Primary) ; Cisplatin (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary)
- Indications Non-small cell lung cancer; Squamous cell cancer
- Focus Therapeutic Use
- Sponsors Mirati Therapeutics
- 19 May 2023 Number of treatment arms have been increased from 2 to 3 by the addition of Experimental: Cohort E arm. Pemetrexed, Cisplatin/Carboplatin have also been added to chemotherapy to be given along with study drug.
- 19 May 2023 Planned End Date changed from 23 Dec 2025 to 1 Dec 2026.
- 19 May 2023 Planned primary completion date changed from 23 Jun 2025 to 1 Jun 2026.