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A Randomized, Double-blind, Placebo-controlled, Clinical Trial of a 3-dose, 28-day Regimen of PfSPZ Vaccine in Healthy, Adult Participants to Determine Safety, Tolerability and Efficacy Against Heterologous Plasmodium Falciparum Controlled Human Malaria Infection Conducted 3 or 12 Weeks After Immunization

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A Randomized, Double-blind, Placebo-controlled, Clinical Trial of a 3-dose, 28-day Regimen of PfSPZ Vaccine in Healthy, Adult Participants to Determine Safety, Tolerability and Efficacy Against Heterologous Plasmodium Falciparum Controlled Human Malaria Infection Conducted 3 or 12 Weeks After Immunization

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 27 Nov 2024

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At a glance

  • Drugs Malaria vaccine live attenuated-Sanaria (Primary)
  • Indications Falciparum malaria
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Sanaria

    • Most Recent Events

    • 25 Nov 2024 According to ClinicalTrials.gov by the U.S. National Institutes of Health, the one efficacy primary endpoints has removed.
    • 05 Oct 2023 Status changed from active, no longer recruiting to discontinued.
    • 06 Jun 2023 Status changed from recruiting to active, no longer recruiting.

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