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A Phase II Trial of Tislelizumab in Combination With Sitravatinib for Recurrent/Metastatic Cervical Cancer After Platinum-Based Chemotherapy

Trial Profile

A Phase II Trial of Tislelizumab in Combination With Sitravatinib for Recurrent/Metastatic Cervical Cancer After Platinum-Based Chemotherapy

Status: Withdrawn prior to enrolment
Phase of Trial: Phase II

Latest Information Update: 03 Jul 2023

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At a glance

  • Drugs Sitravatinib (Primary) ; Tislelizumab (Primary)
  • Indications Adenocarcinoma; Adenosquamous carcinoma; Cervical cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms ITTACC

Most Recent Events

  • 28 Jun 2023 According to clinicaltrials.gov, the study was stopped: BeiGene has withdrawn their support owing to sitravatinib supply concerns. Mirati is ceasing further development of sitravatinib owing to the negative results of the SAPPHIRE trial which used sitravatinib in 2nd line met NSCLC setting.
  • 28 Jun 2023 Status changed from not yet recruiting to withdrawn prior to enrolment.
  • 31 Jan 2023 Planned initiation date changed from 1 Dec 2022 to 1 Mar 2023.

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