Trial Profile

A Phase II Trial of De-escalated PTCy and Ruxolitinib for GVHD Prophylaxis in Patients Undergoing Reduced Intensity Conditioning Allogeneic HCT

Status: Suspended

Phase of Trial: Phase II

Latest Information Update: 24 Oct 2025

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At a glance

Drugs Cyclophosphamide (Primary) ; Mycophenolate mofetil (Primary) ; Ruxolitinib (Primary) ; Tacrolimus (Primary) ; Tacrolimus (Primary)
Indications Graft-versus-host disease
Focus Therapeutic Use

Most Recent Events

21 Oct 2025 Planned End Date changed from 15 Sep 2025 to 15 Sep 2026.
21 Oct 2025 Planned primary completion date changed from 15 Sep 2025 to 15 Sep 2026.
21 Oct 2025 Status changed from recruiting to suspended, because enrollment was completed but is going to expand with pending protocol amendment.

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