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A Phase II Trial of De-escalated PTCy and Ruxolitinib for GVHD Prophylaxis in Patients Undergoing Reduced Intensity Conditioning Allogeneic HCT

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A Phase II Trial of De-escalated PTCy and Ruxolitinib for GVHD Prophylaxis in Patients Undergoing Reduced Intensity Conditioning Allogeneic HCT

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 18 Feb 2025

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At a glance

  • Drugs Cyclophosphamide (Primary) ; Mycophenolate mofetil (Primary) ; Ruxolitinib (Primary) ; Tacrolimus (Primary) ; Tacrolimus (Primary)
  • Indications Graft-versus-host disease
  • Focus Therapeutic Use

    • Most Recent Events

    • 01 Oct 2024 Planned End Date changed from 15 Dec 2025 to 15 Sep 2025.
    • 01 Oct 2024 Planned primary completion date changed from 15 Dec 2025 to 15 Sep 2025.
    • 29 Aug 2023 Planned End Date changed from 15 Jul 2025 to 15 Dec 2025.

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