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MAGNETISMM-6: AN OPEN-LABEL, 2-ARM, MULTICENTER, RANDOMIZED PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ELRANATAMAB (PF-06863135) + DARATUMUMAB + LENALIDOMIDE OR ELRANATAMAB + LENALIDOMIDE VERSUS DARATUMUMAB + LENALIDOMIDE + DEXAMETHASONE IN TRANSPLANT-INELIGIBLE PARTICIPANTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA

Trial Profile

MAGNETISMM-6: AN OPEN-LABEL, 2-ARM, MULTICENTER, RANDOMIZED PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ELRANATAMAB (PF-06863135) + DARATUMUMAB + LENALIDOMIDE OR ELRANATAMAB + LENALIDOMIDE VERSUS DARATUMUMAB + LENALIDOMIDE + DEXAMETHASONE IN TRANSPLANT-INELIGIBLE PARTICIPANTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 31 Jul 2025

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At a glance

  • Drugs Daratumumab (Primary) ; Elranatamab (Primary) ; Lenalidomide (Primary) ; Dexamethasone
  • Indications Multiple myeloma
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms MagnetisMM-6
  • Sponsors Pfizer

Most Recent Events

  • 23 Apr 2025 According to a Pfizer media release, the data from this trial will be presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting.
  • 19 Sep 2024 Planned number of patients changed from 1116 to 966.
  • 09 Nov 2023 This trial has been suspended in Spain, according to European Clinical Trials Database record.

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