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A FIH, Single Arm, Open Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of Autologous CAR T Cells Targeting BT-001 in Patients With Advanced Solid Tumors

Trial Profile

A FIH, Single Arm, Open Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of Autologous CAR T Cells Targeting BT-001 in Patients With Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 20 Oct 2023

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At a glance

  • Drugs B4T2 001 (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Adenocarcinoma; Advanced breast cancer; Colorectal cancer; Gastric cancer; Non-small cell lung cancer; Oesophageal cancer; Pancreatic cancer; Solid tumours
  • Focus Adverse reactions; First in man
  • Most Recent Events

    • 17 Oct 2023 Status changed from active, no longer recruiting to completed, aaccording to a Bio4t2 media release.
    • 10 Oct 2023 Status changed from recruiting to active, no longer recruiting.
    • 10 Jan 2023 According to a Bio4t2 media release, first patient has been dosed in this study.

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