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A Single-center, Single-arm, Open-label, Exploratory Study Evaluating Fruquintinib Combined With Sintilimab in Second-line Treatment of Patients With Advanced Gastric or Gastro-esophageal Junction Adenocarcinoma

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A Single-center, Single-arm, Open-label, Exploratory Study Evaluating Fruquintinib Combined With Sintilimab in Second-line Treatment of Patients With Advanced Gastric or Gastro-esophageal Junction Adenocarcinoma

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Sep 2024

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At a glance

  • Drugs Fruquintinib (Primary) ; Sintilimab (Primary)
  • Indications Adenocarcinoma; Gastric cancer; HER2 negative breast cancer; Oesophageal cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 13 Sep 2024 Planned primary completion date changed from 1 Dec 2023 to 1 Dec 2024.
    • 13 Sep 2024 Status changed from not yet recruiting to active, no longer recruiting.
    • 20 Jan 2024 According to Results presented at the 2024 Gastrointestinal Cancers Symposium, an optimal Simon two-stage design was employed: if more than 1 pt achieved objective responses in the first stage (n = 7), the study would proceed to the second stage and enroll an additional 19 pts; otherwise, the study would be terminated.

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