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A Phase 1, Open-Label, Parallel-Group, Single-Dose Adaptive Study to Evaluate the Safety and Pharmacokinetics of AT-527 in Adult Subjects With Normal and Impaired Renal Function Sub-Study: Effects of Probenecid on the Pharmacokinetics of AT-527 in Healthy Adult Subjects.

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Trial Profile

A Phase 1, Open-Label, Parallel-Group, Single-Dose Adaptive Study to Evaluate the Safety and Pharmacokinetics of AT-527 in Adult Subjects With Normal and Impaired Renal Function Sub-Study: Effects of Probenecid on the Pharmacokinetics of AT-527 in Healthy Adult Subjects.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 16 May 2025

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At a glance

  • Drugs Bemnifosbuvir (Primary) ; Probenecid (Primary)
  • Indications COVID 2019 infections; Hepatitis C
  • Focus Pharmacokinetics
  • Sponsors Atea Pharmaceuticals

Most Recent Events

  • 12 May 2025 According to an Atea Pharmaceuticals, Inc. media release, company announced that results from this trial were presented at the European Association for the Study of the Liver (EASL) Congress 2025 from May 7-10 in Amsterdam, Netherlands.
  • 31 Jul 2024 Status changed from recruiting to completed.
  • 01 Feb 2024 Planned End Date changed from 20 Nov 2023 to 23 Apr 2024.

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