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A Phase 2a, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Dosing of Exidavnemab in Patients With Mild to Moderate Parkinson's Disease on Stable Symptomatic Parkinson's Disease Medication and in Patients With Multiple System Atrophy

Trial Profile

A Phase 2a, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Dosing of Exidavnemab in Patients With Mild to Moderate Parkinson's Disease on Stable Symptomatic Parkinson's Disease Medication and in Patients With Multiple System Atrophy

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 16 Mar 2026

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At a glance

  • Drugs Exidavnemab (Primary)
  • Indications Parkinson's disease
  • Focus Therapeutic Use
  • Acronyms EXIST

Most Recent Events

  • 10 Mar 2026 Planned End Date changed from 16 Mar 2026 to 17 Aug 2026.
  • 10 Mar 2026 Planned primary completion date changed from 16 Mar 2026 to 17 Aug 2026.
  • 10 Mar 2026 Status changed from recruiting to active, no longer recruiting.

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