Trial Profile

A Phase 1a/1b, Open-Label, Multi-Center, Dose Escalation and Expansion Study of HFB200603 (Anti-BTLA Antibody) as a Single Agent and in Combination With Tislelizumab (Anti-PD-1 Antibody) in Adult Patients With Advanced Solid Tumors

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 24 Sep 2025

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At a glance

Drugs HFB 200603 (Primary) ; Tislelizumab (Primary)
Indications Colorectal cancer; Gastric cancer; Malignant melanoma; Non-small cell lung cancer; Renal cell carcinoma; Solid tumours
Focus Adverse reactions; First in man
Sponsors HiFiBiO

24 Sep 2025 New source identified and integrated (Clinical Trials Information System: CTIS2022-502891-22-00).
25 Apr 2023 Status changed from not yet recruiting to recruiting.
15 Mar 2023 Status changed from planning to not yet recruiting.

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