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A Phase 1a/1b, Open-Label, Multi-Center, Dose Escalation and Expansion Study of HFB200603 (Anti-BTLA Antibody) as a Single Agent and in Combination With Tislelizumab (Anti-PD-1 Antibody) in Adult Patients With Advanced Solid Tumors

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A Phase 1a/1b, Open-Label, Multi-Center, Dose Escalation and Expansion Study of HFB200603 (Anti-BTLA Antibody) as a Single Agent and in Combination With Tislelizumab (Anti-PD-1 Antibody) in Adult Patients With Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 16 Apr 2025

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At a glance

  • Drugs HFB 200603 (Primary) ; Tislelizumab (Primary)
  • Indications Colorectal cancer; Gastric cancer; Malignant melanoma; Non-small cell lung cancer; Renal cell carcinoma; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors HiFiBiO

    • Most Recent Events

    • 25 Apr 2023 Status changed from not yet recruiting to recruiting.
    • 15 Mar 2023 Status changed from planning to not yet recruiting.
    • 06 Jan 2023 According to a HiFiBiO media release, the U.S. Food and Drug Administration (FDA) has cleared the Investigational New Drug (IND) application for HFB200603.

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