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A retrospective, cohort study analyzing difference in clinical and endoscopic outcomes for UST or VDZ as a monotherapy compared to a combination with thiopurines or methotrexate

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Trial Profile

A retrospective, cohort study analyzing difference in clinical and endoscopic outcomes for UST or VDZ as a monotherapy compared to a combination with thiopurines or methotrexate

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 29 Nov 2022

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At a glance

  • Drugs Ustekinumab (Primary) ; Vedolizumab (Primary) ; Methotrexate; Purines
  • Indications Crohn's disease; Ulcerative colitis
  • Focus Therapeutic Use

Most Recent Events

  • 29 Nov 2022 New trial record
  • 11 Oct 2022 Primary endpoint has not been met. (clinical remission or response as calculated by partial MAYO score (remission 3, response is a decrease 1) for UC or Harvey Bradshaw Index for CD (remission 5, response is a decrease 2) at week 52, as per Results presented at the 30th United European Gastroenterology Week
  • 11 Oct 2022 Primary endpoint has not been met. (clinical remission or response as calculated by partial MAYO score (remission 3, response is a decrease 1) for UC or Harvey Bradshaw Index for CD (remission 5, response is a decrease 2) at week 26), as per Results presented at the 30th United European Gastroenterology Week

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