Trial Profile

A Two-Part Phase 1b Study Evaluating the Combination of Tazemetostat and CPX-351 (Part 1) and Palbociclib Pre-Treatment Followed by CPX-351 (Part 2) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 22 Mar 2026

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At a glance

Drugs Cytarabine/daunorubicin (Primary) ; Palbociclib (Primary) ; Tazemetostat (Primary)
Indications Acute myeloid leukaemia
Focus Adverse reactions

18 Feb 2026 Planned End Date changed from 1 Jan 2026 to 1 Jan 2029.
18 Feb 2026 Planned primary completion date changed from 1 Jan 2026 to 1 Jan 2028.
18 Feb 2026 Status changed from suspended to recruiting.

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