Trial Profile

A Proof of Concept Study of TBio-4101 (an Autologous Selected and Expanded Tumor Infiltrating Lymphocyte [TIL] Therapy) Using Short-Term Cultured, Selected Autologous TIL Following a Lymphodepleting Chemotherapy Regimen and Followed by IL-2 for Patients With Relapsed or Refractory Melanoma (Phase 1)

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 09 Apr 2026

Price :

$35 ^*

Note:

Adis is an information provider.
Final gross price and currency may vary according to local VAT and billing address.
Your purchase entitles you to full access to the information contained in our trial profile at the time of purchase.
A link to download a PDF version of the trial profile will be included in your email receipt.

At a glance

Drugs Cyclophosphamide (Primary) ; Interleukin-2 (Primary) ; TIDAL-01 (Primary) ; Fludarabine; Mesna
Indications Eye neoplasms; Malignant melanoma; Skin cancer; Uveal melanoma
Focus First in man; Proof of concept; Therapeutic Use

02 Apr 2026 Actual Primary Completion Date is 3 Dec 2024.
02 Apr 2026 Status changed from discontinued to completed.
07 Jan 2026 Planned primary completion date changed from 1 Dec 2025 to 1 Jun 2026.

If your organization or you do not have a subscription, try one of the following:

Contacting your organization’s admin about adding this content to your AdisInsight subscription
Buying a PDF version of any individual profile
Request a free trial (opens in a new window)

If your organization has a subscription, there are several access options, even while working remotely:

Working within your organization’s network
Login with username/password or try to access via your institution
Persisted access using your organization’s identifier stored in your user browser for 90 days

For assistance, contact us at asktheexpert.adisinsight@springer.com