A Phase II Study of SHR-A1811 Monotherapy or Combined With Pyrotinib Maleate as Neoadjuvant Treatment in HER2-positive Breast Cancer Patients
Latest Information Update: 10 Jan 2025
At a glance
- Drugs Pyrotinib (Primary) ; Trastuzumab rezetecan (Primary)
- Indications Advanced breast cancer; Early breast cancer; HER2 positive breast cancer
- Focus Therapeutic Use
Most Recent Events
- 05 Jul 2024 Numbers of arms changed from 1 to 2. Experimental: SHR-A1811 arm added to study protocol. Interventional Study Model changed from Single Group Assignment to Parallel Assignment. Allocation changed to Non-Randomized. Planned number of patients also increased.
- 05 Jul 2024 Planned number of patients changed from 61 to 65.
- 05 Jul 2024 Planned End Date changed from 28 Feb 2029 to 28 Feb 2030.