A Phase II/III Multicenter Randomized, Double-Blind, Placebo-Controlled Platform Trial of Potential Disease Modifying Therapies Utilizing Biomarker, Cognitive, and Clinical Endpoints in Dominantly Inherited Alzheimer's Disease
Latest Information Update: 17 Feb 2026
At a glance
- Drugs Etalanetug (Primary) ; Lecanemab (Primary)
- Indications Alzheimer's disease
- Focus Therapeutic Use
- Acronyms DIAN-TU; Tau NexGen Study
Most Recent Events
- 27 Oct 2025 According to an Eisai media release, since January 2022, the Tau NexGen clinical study is ongoing for Dominantly Inherited AD (DIAD), that is conducted by Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU), led by Washington University School of Medicine in St. Louis.
- 03 Jul 2024 Planned End Date changed from 1 Oct 2027 to 1 Jul 2028.
- 03 Jul 2024 Planned primary completion date changed from 1 Jul 2027 to 1 Apr 2028.