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A Phase 3, Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Who Are Virologically Suppressed on Antiretroviral Therapy

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Trial Profile

A Phase 3, Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Who Are Virologically Suppressed on Antiretroviral Therapy

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 19 Mar 2025

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At a glance

  • Drugs Doravirine/islatravir (Primary) ; Antiretrovirals
  • Indications HIV-1 infections
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 12 Mar 2025 According to Merck & Co media release, data from this trial will be presented at the 32nd Conference on Retroviruses and Opportunistic Infections (CROI)
  • 12 Mar 2025 Results presented in the Merck & Co Media Release
  • 19 Dec 2024 According to Merck Media Release, company is planning to present detailed findings from these trials at a future scientific congress and will also plan to file these data with regulatory authorities.

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