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Phase I/II study on safety and efficacy of NMS-01940153E in adult patients with unresectable hepatocellular carcinoma (HCC) previously treated with systemic therapy

Trial Profile

Phase I/II study on safety and efficacy of NMS-01940153E in adult patients with unresectable hepatocellular carcinoma (HCC) previously treated with systemic therapy

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 14 May 2025

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At a glance

  • Drugs S 81694 (Primary)
  • Indications Carcinoma; Liver cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Nerviano Medical Sciences

Most Recent Events

  • 07 May 2025 Status changed from completed to discontinued.(Reason the study was stopped: In the Phase II part of the study, among the participants evaluable for efficacy, no objective (partial response or clinical response) was observed at the first futility analysis.)
  • 27 Aug 2024 Status changed from active, no longer recruiting to completed.
  • 26 Feb 2024 Planned End Date changed from 25 Mar 2026 to 27 Mar 2025.

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