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A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of LP-108, a BCL-2 Inhibitor, Combined With Azacitidine In Subjects With AML, MDS, CMML

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Trial Profile

A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of LP-108, a BCL-2 Inhibitor, Combined With Azacitidine In Subjects With AML, MDS, CMML

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Feb 2023

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At a glance

  • Drugs Azacitidine (Primary) ; Lacutoclax (Primary)
  • Indications Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Guangzhou Lupeng Pharmaceutical

Most Recent Events

  • 16 Feb 2023 Planned initiation date changed from 10 Dec 2022 to 14 Feb 2023.
  • 16 Feb 2023 Status changed from not yet recruiting to recruiting.
  • 12 Dec 2022 New trial record

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