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Efficacy and Safety of Neoadjuvant Dalpiciclib Combined With Endocrine Therapy in Luminal B/HER2-negative Breast Cancer and Biomarker Analysis: a Single-arm, Open-label Trial

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Trial Profile

Efficacy and Safety of Neoadjuvant Dalpiciclib Combined With Endocrine Therapy in Luminal B/HER2-negative Breast Cancer and Biomarker Analysis: a Single-arm, Open-label Trial

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 16 Jul 2024

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At a glance

  • Drugs Dalpiciclib (Primary) ; Anastrozole; Letrozole
  • Indications HER2 negative breast cancer
  • Focus Therapeutic Use
  • Acronyms DAPATH; PROBE

    • Most Recent Events

    • 04 Jun 2024 Results (n=23)presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 30 Jan 2024 Protocol amended to remove active comparator arm, parallel assignment changed to Single Group Assignment. Planned patient number changed.
    • 30 Jan 2024 Planned number of patients changed from 120 to 30.

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