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A Two-Part, Phase 1, Randomized, Double-blind, Placebo-Controlled, Single Dose Study of the Safety, Tolerability, and Pharmacokinetics of ALN-PNP, an siRNA Targeting PNPLA3, in Healthy Adults and Adult Participants With NAFLD

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A Two-Part, Phase 1, Randomized, Double-blind, Placebo-Controlled, Single Dose Study of the Safety, Tolerability, and Pharmacokinetics of ALN-PNP, an siRNA Targeting PNPLA3, in Healthy Adults and Adult Participants With NAFLD

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 21 Mar 2025

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At a glance

  • Drugs ALN PNP (Primary)
  • Indications Non-alcoholic steatohepatitis
  • Focus Adverse reactions
  • Sponsors Regeneron Pharmaceuticals

    • Most Recent Events

    • 18 Mar 2025 Planned End Date changed from 10 Sep 2025 to 18 Oct 2025.
    • 18 Mar 2025 Planned primary completion date changed from 10 Sep 2025 to 18 Oct 2025.
    • 18 Mar 2025 Status changed from recruiting to active, no longer recruiting.

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