Phase 1 Trial of GPC2-Directed Chimeric Antigen Receptor Autologous T Cells (GPC2 CAR T) for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma
Latest Information Update: 25 Oct 2025
At a glance
- Drugs GPC2 CAR T cell therapy Childrens Hospital of Philadelphia Tmunity Therapeutics (Primary)
- Indications Neuroblastoma; Retinoblastoma
- Focus Adverse reactions; First in man
Most Recent Events
- 21 Oct 2025 Inclusion criteria is updated to add Retinoblastoma as a study indication.
- 21 Oct 2025 Planned number of patients changed from 30 to 45.
- 11 Apr 2025 Planned End Date changed from 30 Jan 2026 to 30 Jan 2030.