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A Phase 1a/1b Study of ELVN-002 for the Treatment of Patients With HER2 Mutant Non-Small Cell Lung Cancer

Trial Profile

A Phase 1a/1b Study of ELVN-002 for the Treatment of Patients With HER2 Mutant Non-Small Cell Lung Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 08 Jul 2025

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At a glance

  • Drugs ELVN-002 (Primary) ; Trastuzumab emtansine; Trastuzumab-deruxtecan
  • Indications Advanced breast cancer; Colorectal cancer; HER2 positive breast cancer; Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; Proof of concept
  • Sponsors Enliven Therapeutics

Most Recent Events

  • 29 Jun 2025 Status changed from recruiting to active, no longer recruiting.
  • 06 Jun 2024 Planned number of patients changed from 178 to 198.
  • 14 May 2024 According to an Enliven Therapeutics media release, company expected to include between approximately 60-100 patients across various lines of therapy with significant follow-up.

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