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A PHASE 1, OPEN-LABEL, 2-PERIOD, FIXED SEQUENCE STUDY TO INVESTIGATE THE ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION OF [14C]PF-07081532 AND TO ASSESS THE ABSOLUTE BIOAVAILABILITY AND FRACTION ABSORBED OF PF-07081532 IN HEALTHY MALE PARTICIPANTS USING A [14C]-MICROTRACER APPROACH

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Trial Profile

A PHASE 1, OPEN-LABEL, 2-PERIOD, FIXED SEQUENCE STUDY TO INVESTIGATE THE ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION OF [14C]PF-07081532 AND TO ASSESS THE ABSOLUTE BIOAVAILABILITY AND FRACTION ABSORBED OF PF-07081532 IN HEALTHY MALE PARTICIPANTS USING A [14C]-MICROTRACER APPROACH

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 26 Sep 2024

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At a glance

  • Drugs Lotiglipron (Primary) ; Lotiglipron (Primary)
  • Indications Obesity; Type 2 diabetes mellitus
  • Focus Pharmacokinetics
  • Sponsors Pfizer

Most Recent Events

  • 22 Mar 2023 Status changed from active, no longer recruiting to completed.
  • 02 Mar 2023 Planned End Date changed from 13 Mar 2023 to 15 Mar 2023.
  • 02 Mar 2023 Planned primary completion date changed from 13 Mar 2023 to 15 Mar 2023.

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