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A Single Arm Phase 2 Study of Y-90 SIRT in Combination with Durvalumab (MEDI 4736) and Gemcitabine/cisplatin in Locally Advanced, Unresectable or Metastatic Intrahepatic Cholangiocarcinoma

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Trial Profile

A Single Arm Phase 2 Study of Y-90 SIRT in Combination with Durvalumab (MEDI 4736) and Gemcitabine/cisplatin in Locally Advanced, Unresectable or Metastatic Intrahepatic Cholangiocarcinoma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 12 Mar 2025

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At a glance

  • Drugs Cisplatin (Primary) ; Durvalumab (Primary) ; Gemcitabine (Primary) ; Yttrium-90 (Primary)
  • Indications Cholangiocarcinoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 02 Feb 2024 Planned primary completion date changed from 1 Dec 2024 to 1 Dec 2026.
  • 15 Nov 2023 Planned initiation date (estimated date for recruitment of the first subject) changed from 1 Sep 2023 to 1 Dec 2023.
  • 21 Aug 2023 Status changed from not yet recruiting to recruiting.

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