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A Multi-center Phase 1/2a Study of Narazaciclib (ON 123300) in Combination With Letrozole as Therapy for the Treatment of Recurrent Metastatic Endometrial Cancer and Other Gynecologic Malignancies

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Trial Profile

A Multi-center Phase 1/2a Study of Narazaciclib (ON 123300) in Combination With Letrozole as Therapy for the Treatment of Recurrent Metastatic Endometrial Cancer and Other Gynecologic Malignancies

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 21 Aug 2024

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At a glance

  • Drugs Letrozole (Primary) ; Narazaciclib (Primary)
  • Indications Breast cancer; Endometrial cancer; Multiple myeloma
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Sponsors Onconova Therapeutics; Traws Pharma

    • Most Recent Events

    • 15 Aug 2024 According to Traws pharma media release, the topline results will be presented at an upcoming medical meeting in H2 2024. And, also company plan to announce the recommended Phase 2 dose (RP2D) and initiate ISTs in multiple myeloma, breast cancer and other indications
    • 02 Apr 2024 According to a Onconova Therapeutics media release, Trawsfynydd Therapeutics has merged with Onconova Therapeutics to form Traws Pharma
    • 12 Dec 2023 According to an Onconova Therapeutics Media Release, data from this was presented at the 65th American Society for Hematology.

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