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A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Pemvidutide in Non-Cirrhotic Subjects With Nonalcoholic Steatohepatitis (NASH)

Trial Profile

A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Pemvidutide in Non-Cirrhotic Subjects With Nonalcoholic Steatohepatitis (NASH)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 04 Mar 2025

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At a glance

  • Drugs Pemvidutide (Primary)
  • Indications Non-alcoholic steatohepatitis
  • Focus Therapeutic Use
  • Acronyms IMPACT trial
  • Sponsors Altimmune
  • Most Recent Events

    • 27 Feb 2025 According to an Altimmune media release, company is on track for top-line data readout in Q2 2025.
    • 15 Oct 2024 According to an Altimmune media release, topline data expected in the second quarter of 2025.
    • 30 Sep 2024 According to an Altimmune media release, company announced completion of patient enrollment in IMPACT trial with top-line efficacy data expected in the second quarter of 2025. Company have received FDA confirmation of the End-of-Phase 2 meeting for our obesity program, which is scheduled for early November 2024. Dr. Mazen Noureddin, M.D., MHSc is the Principal Investigator on the IMPACT trial.

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