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A Phase I, Open-label, Multicenter, Dose-Escalating Study to Evaluate the Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration

Trial Profile

A Phase I, Open-label, Multicenter, Dose-Escalating Study to Evaluate the Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 28 Feb 2024

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At a glance

  • Drugs KH-631 (Primary)
  • Indications Wet age-related macular degeneration
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms VAN-2201
  • Sponsors Chengdu Kanghong Pharmaceutical

Most Recent Events

  • 20 Nov 2023 According to a Chengdu Origen Biotechnology Co Ltd media release, Jeffrey S.Heier, MD, director of the Vitreoretinal Service and Director of Retina Research at Ophthalmic Consultants of Boston and Avner Ingerman, MD, Chief Medical Officer of Vanotech are the principal investigators of this phase 1 study.
  • 20 Nov 2023 According to a Chengdu Origen Biotechnology Co Ltd media release, company announced today the first patient dosed in the VAN-2201 multi-center Phase 1 clinical trial evaluating treatment with KH631 for patients with wet Age-related Macular Degeneration (wet AMD).
  • 17 Aug 2023 Planned End Date changed from 1 May 2027 to 1 Sep 2027.

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