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A Randomized Open-Label Phase 3 Study of XL092 + Nivolumab vs Sunitinib in Subjects With Advanced or Metastatic Non-Clear Cell Renal Cell Carcinoma

Trial Profile

A Randomized Open-Label Phase 3 Study of XL092 + Nivolumab vs Sunitinib in Subjects With Advanced or Metastatic Non-Clear Cell Renal Cell Carcinoma

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 17 Jan 2025

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At a glance

  • Drugs Nivolumab (Primary) ; Zanzalintinib (Primary) ; Sunitinib
  • Indications Renal cell carcinoma
  • Focus Registrational; Therapeutic Use
  • Acronyms STELLAR-304
  • Sponsors Exelixis

Most Recent Events

  • 12 Jan 2025 According to an Exelixis media release, Based on current enrollment status in the trial, the primary endpoint of PFS is expected to be available in the second half of 2025, dependent on study event rates.
  • 04 Jun 2024 Results assessing assessing the efficacy and safety of zanzalintinib, nivolumab versus sunitinib in previously untreated advanced nccRCC, presented at the 60th Annual Meeting of the American Society of Clinical Oncology
  • 24 Oct 2023 Trial design, presented at the 48th European Society for Medical Oncology Congress

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