Trial Profile

A 12-Month, Randomized, Open-Label, Phase IIA Study Evaluating the Safety and Efficacy of Siplizumab in Combination With Belatacept and MPA Compared to Standard of Care Immunosuppression in de Novo Renal Transplant Recipients (ASCEND)

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 07 Oct 2025

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At a glance

Drugs Belatacept (Primary) ; Corticosteroids (Primary) ; Mycophenolic acid (Primary) ; Siplizumab (Primary) ; Antithymocyte globulin; Tacrolimus
Indications Renal transplant rejection
Focus Adverse reactions
Acronyms ASCEND
Sponsors ITBMed Biopharmaceuticals

09 Sep 2025 Planned End Date changed from 1 Oct 2026 to 1 Apr 2026.
09 Sep 2025 Planned primary completion date changed from 1 Jul 2025 to 1 Apr 2026.
17 Apr 2025 Status changed from recruiting to active, no longer recruiting.

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