Trial Profile

A Phase 1/2 Study of Oral IRAK-4 Inhibitor CA-4948 in Combination With Pembrolizumab and Stereotactic Radiosurgery in Patients With Melanoma Brain Metastases

Status: Suspended

Phase of Trial: Phase I/II

Latest Information Update: 09 Apr 2025

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At a glance

Drugs Emavusertib (Primary) ; Pembrolizumab (Primary)
Indications Brain metastases; Malignant melanoma
Focus Therapeutic Use

Most Recent Events

04 Apr 2025 Planned initiation date changed from 1 Feb 2025 to 1 Apr 2025.
04 Apr 2025 Status changed from recruiting to suspended.
16 Jan 2025 Planned initiation date (estimated date for recruitment of the first subject) changed from 1 Dec 2024 to 1 Feb 2025.

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