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A Phase Ib/II Clinical Study of SI-B001+SI-B003 Dual-drug No-combination or Combined Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma

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Trial Profile

A Phase Ib/II Clinical Study of SI-B001+SI-B003 Dual-drug No-combination or Combined Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 20 Aug 2025

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At a glance

  • Drugs Danvilostomig (Primary) ; Izalontamab (Primary) ; Carboplatin; Cisplatin; Fluorouracil
  • Indications Head and neck cancer; Squamous cell cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Sichuan Baili Pharmaceutical

Most Recent Events

  • 06 Aug 2025 Planned number of patients changed from 40 to 130.
  • 06 Aug 2025 Planned primary completion date changed from 1 Jun 2025 to 1 Dec 2025.
  • 18 Dec 2024 Planned End Date changed from 1 Dec 2024 to 1 Dec 2025.

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