An International, Phase 3, Randomized, Multicenter, Open-label Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With KIT Exon 11 and Co-occurring KIT Exons 17 and/or 18 Mutations Who Were Previously Treated With Imatinib
Latest Information Update: 11 Apr 2025
At a glance
- Drugs Ripretinib (Primary) ; Sunitinib
- Indications Gastrointestinal stromal tumours
- Focus Registrational; Therapeutic Use
- Acronyms INSIGHT
- Sponsors Deciphera Pharmaceuticals
Most Recent Events
- 25 Jan 2025 Trial design were presented at the 2025 Gastrointestinal Cancers Symposium.
- 20 Jan 2024 Trial design presented at the 2024 Gastrointestinal Cancers Symposium
- 30 Oct 2023 According to a Deciphera Pharmaceuticals media release, company Initiated this study by opening the first sites for enrollment comparing QINLOCK versus sunitinib in second-line GIST patients with mutations in KIT exon 11 and 17/18.