A Phase I/II Trial of Botensilimab, Balstilimab and Regorafenib (BBR) in Patients With Microsatellite Stable (MSS) Metastatic Colorectal Cancer Who Progressed on Prior Chemotherapy
Latest Information Update: 04 Feb 2026
At a glance
- Drugs Balstilimab (Primary) ; Botensilimab (Primary) ; Regorafenib (Primary)
- Indications Adenocarcinoma; Colorectal cancer
- Focus Adverse reactions; Therapeutic Use
Most Recent Events
- 28 Jan 2026 Planned End Date changed from 27 Dec 2025 to 25 Aug 2026.
- 12 Nov 2025 Planned End Date changed from 27 Oct 2025 to 27 Dec 2025.
- 05 Nov 2025 Actual primary completion date changed to 10 May 2025.