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A Phase I/II Trial of Botensilimab, Balstilimab and Regorafenib (BBR) in Patients With Microsatellite Stable (MSS) Metastatic Colorectal Cancer Who Progressed on Prior Chemotherapy

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Trial Profile

A Phase I/II Trial of Botensilimab, Balstilimab and Regorafenib (BBR) in Patients With Microsatellite Stable (MSS) Metastatic Colorectal Cancer Who Progressed on Prior Chemotherapy

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 17 Nov 2025

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At a glance

Most Recent Events

  • 12 Nov 2025 Planned End Date changed from 27 Oct 2025 to 27 Dec 2025.
  • 05 Nov 2025 Actual primary completion date changed to 10 May 2025.
  • 25 Jul 2025 According to the Agenus Media Release, company announced data from this study has been accepted for presentation at the European Society for Medical Oncology (ESMO) Congress 2025, taking place in Berlin, Germany from October 17-21.

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