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A Phase II Study of Induction Tucatinib and Trastuzumab With Total Neoadjuvant Therapy for Locally Advanced HER2-amplified Rectal Adenocarcinoma

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Trial Profile

A Phase II Study of Induction Tucatinib and Trastuzumab With Total Neoadjuvant Therapy for Locally Advanced HER2-amplified Rectal Adenocarcinoma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 26 Dec 2024

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At a glance

  • Drugs Trastuzumab (Primary) ; Tucatinib (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Rectal cancer
  • Focus Therapeutic Use

Most Recent Events

  • 12 Apr 2024 Chemotherapy CAPOX is replaced by FOLFOX.
  • 06 Jan 2023 New trial record

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